Grubb Lab
MRC Centre for Developmental Neurobiology
King's College London
Grubb Lab,
MRC Centre for Developmental Neurobiology,
King's College London, 
New Hunt's House,
Guy's Hospital Campus, 
London.
SE1 1UL
UK
 
 
 
 





  
Home      Chand publications
Primary research papers

IR Thompson*, AN Chand*, PJ King, O Ansorge, N Karavitaki, CA Jones, D Rahmutula, DG Gardner, V Zivkovic, CP Wheeler-Jones, IM McGonnell, M Korbonits, RA Anderson, JA Wass, AS McNeilly, RC Fowkes (2012) Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a role for C-type natriuretic peptide.  Endocrine-Related Cancer, 19 (4), 497 – 508.  Pubmed  Full Text
*Joint first authors
 
IR Thompson, AN Chand, KC Jonas, JM Burrin, ME Steinhelper, CP Wheeler-Jones, CA McArdle, RC Fowkes (2009) Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, aT3-1 and LβT2 gonadotroph cells. Journal of Endocrinology, 203 (2), 215 – 229.  Pubmed


In preparation:

AN Chand, MV Patel, LR O’Shea, IR Thompson, O Ansorge, V Sharp, RA Anderson, JAH Wass, JM Burrin, AS McNeilly, IM McGonnell, RC Fowkes: Expression and activity of calcium/calmodulin-dependent protein kinase genes in models of mammalian anterior pituitary development.

ER Davies, AN Chand, IR Thompson, M Korbonits, RC Fowkes: Expression and function of an endocannabinoid system in immortalized pituitary gonadotropes and somatotropes.

AE Michael, N Prathalingam, AN Chand, SM Kay, EL Atkinson, RJ Webb, H Feitsma, LM Thurston: Mammalian semen contains hydrophobic modulators of type 1 11β-hydroxysteroid 2-dehydrogenase (HSD11B1) which correlate with ejaculated sperm viability and male fertility. In revision.

KC Jonas, IR Thompson, AN Chand, A Waltho, A Mukherjee, RC Fowkes: C-type natriuretic peptide stimulates cGMP-independent pathways to reveal an alternative paradigm for particulate guanylyl cyclase signalling.

 
Published abstracts
AN Chand and MS Grubb (2011) Activity-dependent plasticity in dopaminergic neurons of the olfactory bulb. Program No. 331.01. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online.
 
AN Chand, SE Akbareian, IM McGonnell and RC Fowkes (2010) Fish and Chicks: C-type natriuretic peptide and the development of the pituitary gland in Gallus gallus and Danio rerioAbstract of 92nd Annual Meeting of the Endocrine Society, San Diego, 2010, P2-308.  

AN Chand, IR Thompson, SE Akbareian, S Toro, RA Anderson, AS McNeilly, IM McGonnell, RC Fowkes (2010) Developmental and Functional Role of Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Isoforms in Normal Human Fetal Pituitary, LβT2 Gonadotropes and Zebrafish Neuroendocrine Tissues.  Abstract of 92nd Annual Meeting of the Endocrine Society, San Diego, 2010, P2-296.  

AN Chand, SE Akbareian, A McSloy, D Renshaw, IM McGonnell and RC Fowkes (2010) Fish and Chicks: C-type natriuretic peptide and the development of the pituitary gland in Gallus gallus and Danio rerioEndocrine Abstracts (2010) 21, P291.  Abstract

AN Chand, SE Akbareian, I Thompson, R Anderson, AS McNeilly, IM McGonnell, RC Fowkes (2009) Expression of CaMKII isoforms in human foetal and Danio rerio neuroendocrine tissues. Abstract of the Society for Developmental Biology 68th Annual Meeting, San Francisco, 2009, #331.  

AN Chand, SE Akbareian, IM McGonnell, RC Fowkes (2009) Cloning and expression of calcium/calmodulin-dependent protein kinase II isoforms in the developing zebrafish (Danio rerio). Endocrine Abstracts (2009) 19, P224.  Abstract

AN Chand, IM McGonnell, RC Fowkes (2008) Transcriptional regulation of the human guanylyl cyclase-B (GC-B) promoter in pituitary cell lines and primary pituitary cells. Abstract of the International Congress of Endocrinology meeting, Rio de Janeiro, 2008, PO0970.  

AN Chand, IM McGonnell, RC Fowkes (2008) Transcriptional regulation of the human guanylyl cyclase-B (GC-B) promoter in gonadotroph and somatotroph cell lines.  Endocrine Abstracts (2008) 15, P-262.  Abstract

RC Fowkes, KC Jonas, IR Thompson, AN Chand, O Ansorge & JAH Wass (2008) The new biology of pituitary natriuretic peptides: novel signalling from guanylyl cyclase-B receptors.  Endocrine Abstracts (2008) 15, S33.  Abstract

IR Thompson, KC Jonas, AN Chand, CJ Wheeler-Jones, RC Fowkes (2007) Evidence for a local natriuretic peptide system in pituitary GH3 somatotropes. Abstract of 10th International Pituitary Congress, Chicago, 2007. HT2.

KC Jonas, IR Thompson, AN Chand, RC Fowkes (2007) C-Type Natriuretic Peptide (CNP) Stimulation of Mitogen-Activated Protein Kinase (MAPK) Phosphorylation in GH3 Somatotropes Suggests a Novel Paradigm for Guanylyl Cyclase-B (GC-B) Signalling. Abstract of 88th Annual Meeting of the Endocrine Society, Toronto, 2007, P2-614.

KC Jonas, IR Thompson, AN Chand, RC Fowkes (2007) C-Type Natriuretic Peptide (CNP)-Stimulated Phosphorylation of Mitogen Activated Protein Kinases (MAPK) in LbT2 Pituitary Gonadotropes: A cGMP-Independent Mechanism? Abstract of 88th Annual Meeting of the Endocrine Society, Toronto, 2007, P1-397.

KC Jonas, IR Thompson, AN Chand, RC Fowkes (2007) Phosphorylation of MAPK family proteins by C-type natriuretic peptide (CNP) in LbT2 gonadotrophs – a novel cyclic GMP-independent effect? Abstract of the British Endocrine Societies Meeting, Birmingham, 2007, P-245.  Abstract

KC Jonas, IR Thompson, AN Chand, RC Fowkes (2006) Novel activation of MAPK family proteins in pituitary GH3 somatotrophs and aT3-1 gonadotrophs by C-type natriuretic peptide. Abstract of 197th Annual Meeting of the Society for Endocrinology, London, 2006, OC-20.  Abstract

KC Jonas, IR Thompson, AN Chand, RC Fowkes (2006) Novel activation of MAPK family members by C-type natriuretic peptide in anterior pituitary cell lines. Abstract from the 16th International Meeting of Regulatory Peptides, Hakone, Japan, 2006.

SM Mirczuk, B Poulet, AN Chand, JM Burrin, & RC Fowkes (2005) Expression and function of NR5A1, NR5A2 and NR0B1 in mediating gonadotrophin-releasing hormone (GnRH) function in onadotrophs cell lines. Endocrine Abstracts,Society for Endocrinology Annual Meeting 2005 Vol. 10.  Abstract

LM Thurston, JM Busby, AN Chand, SM Kay, L Wilfling and AE Michael (2004) The effect of modulators of 11β-hydroxysteroid dehydrogenase (11βHSD) in porcine seminal plasma on sperm preservation at room temperature. International Congress of Endocrinology, Lisbon, Portugal; 1-4 September.

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